First I recall time served on the inpatient Cardiology service in residency. Then we review the evidence for salt and fluid restriction in acute and chronic heart failure.
Aliti GB, Rabelo ER, Clausell N, Rohde LE, Biolo A, Beck-da-Silva L. Aggressive fluid and sodium restriction in acute decompensated heart failure: a randomized clinical trial. JAMA Intern Med. 2013 Jun 24;173(12):1058-64.
Herrmann JJ, Brunner-La Rocca HP, Baltussen LEHJM, Beckers-Wesche F, Bekkers SCAM, Bellersen L, van Eck JWM, Hassing HC, Jaarsma T, Linssen GCM, Pisters R, Sanders-van Wijk S, Verdijk MHI, Handoko ML, van der Meer P, Verbrugge FH, Januzzi JL Jr, Bayés-Genís A, Nieuwlaat R, Rodwell L, Gommans DHF, van Kimmenade RRJ. Liberal fluid intake versus fluid restriction in chronic heart failure: a randomized clinical trial. Nat Med. 2025 Jun;31(6):2062-2068.
Hsu SM, Lin YH, Lin YC, Liu SJ, Liu CJ, Hung CL, Wang TJ. Fluid intake impact on heart failure: Systematic review and meta-analysis with trial sequential analysis. J Formos Med Assoc. 2025 Jul;124(7):650-659.
Mullens W, Damman K, Dhont S, Banerjee D, Bayes-Genis A, Cannata A, Chioncel O, Cikes M, Ezekowitz J, Flammer AJ, Martens P, Mebazaa A, Mentz RJ, Miró Ò, Moura B, Nunez J, Ter Maaten JM, Testani J, van Kimmenade R, Verbrugge FH, Metra M, Rosano GMC, Filippatos G. Dietary sodium and fluid intake in heart failure. A clinical consensus statement of the Heart Failure Association of the ESC. Eur J Heart Fail. 2024 Apr;26(4):730-741.
Urban S, Fułek M, Błaziak M, Fułek K, Iwanek G, Jura M, Grzesiak M, Szymański O, Stańczykiewicz B, Ptaszkowski K, Zymlinski R, Ponikowski P, Biegus J. Role of dietary sodium restriction in chronic heart failure: systematic review and meta-analysis. Clin Res Cardiol. 2024 Sep;113(9):1331-1342.
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About
Evidence-Based Medicine
with flare
Hello friends! Just a reminder that even though I work at Best Boise Hospital, my opinions, expressions, perseverations, and titillations, are my own and not reflective of any other entity or person I might be affiliated with.
AND! As I'm trying to limit episodes to a digestible length, we won't be covering EVERYTHING about every topic or even every paper. Consider that an unabridged version would be at least 3 hours a pop, shoot me now...
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